Menopausal hormone therapy and risk of dementia: health insurance database in South Korea-based retrospective cohort study.

ABSTRACT:

Introduction

Menopausal hormone therapy (MHT) is used to alleviate the symptoms associated with menopause, despite the lack of recommendations for MHT in preventing dementia. Recent nationwide studies have explored the association between MHT and dementia risk, but the findings remain limited. This study aims to investigate the association between MHT and the incidence of Alzheimer's disease (AD) and non-AD dementia using national population data from Korea.

Methods

We conducted a retrospective study using data from the National Health Insurance Service in Korea between January 1, 2002, and December 31, 2019. Women over 40 years were eligible for this study and classified into the MHT or non-MHT groups. The MHT group consisted of women who used Tibolone (TIB), combined estro

SUBMITTER: Yuk JS 

PROVIDER: S-EPMC10512830 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature