Dietary food patterns as determinants of the gut microbiome-endocannabinoidome axis in humans.

ABSTRACT: The gut microbiota and the endocannabinoidome (eCBome) play important roles in regulating energy homeostasis, and both are closely linked to dietary habits. However, the complex and compositional nature of these variables has limited our understanding of their interrelationship. This study aims to decipher the interrelation between dietary intake and the gut microbiome-eCBome axis using two different approaches for measuring dietary intake: one based on whole food and the other on macronutrient intakes. We reveal that food patterns, rather than macronutrient intakes, were associated with the gut microbiome-eCBome axis in a sample of healthy men and women (n = 195). N-acyl-ethanolamines (NAEs) and gut microbial families were correlated with intakes of vegetables, refined grains, olive oil a

SUBMITTER: Castonguay-Paradis S 

PROVIDER: S-EPMC10514042 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature