Virucidal activity of three standard chemical disinfectants against Ebola virus suspended in tripartite soil and whole blood.

ABSTRACT: Proper disinfection and inactivation of highly pathogenic viruses is an essential component of public health and prevention. Depending on environment, surfaces, and type of contaminant, various methods of disinfection must be both efficient and available. To test both established and novel chemical disinfectants against risk group 4 viruses in our maximum containment facility, we developed a standardized protocol and assessed the chemical inactivation of the two Ebola virus variants Mayinga and Makona suspended in two different biological soil loads. Standard chemical disinfectants ethanol and sodium hypochlorite completely inactivate both Ebola variants after 30 s in suspension at 70% and 0.5% v/v, respectively, concentrations recommended for disinfection by the World Health Organization.

SUBMITTER: Jonsdottir HR 

PROVIDER: S-EPMC10514052 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature