Telomere length as a marker of changes in body composition and fractures-an analysis of data from the NHANES 2001-2002.

ABSTRACT:

Purpose

There has been an association between changes in body composition, fracture incidence, and age in previous studies. Telomere length (TL) has been proposed as a biomarker of aging. However, the relationship between body composition, fractures, and TL has rarely been studied. Therefore, this study aimed to investigate the correlation between TL and body composition and fractures.Patients and methods: 20950 participants from the 2001-2002 National Health and Nutrition Examination Survey (NHANES) were included in the final analysis. In NHANES, body compositions were measured with DXA, and TL was determined with quantitative PCR. Correlation analysis of TL and body composition was conducted using multivariate weighted linear regression and logistic regression models.

Results<

SUBMITTER: Guo Y 

PROVIDER: S-EPMC10514483 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature