Evaluation of synthetically generated computed tomography for use in transcranial focused ultrasound procedures.

ABSTRACT:

Purpose

Transcranial focused ultrasound (tFUS) is a therapeutic ultrasound method that focuses sound through the skull to a small region noninvasively and often under magnetic resonance imaging (MRI) guidance. CT imaging is used to estimate the acoustic properties that vary between individual skulls to enable effective focusing during tFUS procedures, exposing patients to potentially harmful radiation. A method to estimate acoustic parameters in the skull without the need for CT is desirable.

Approach

We synthesized CT images from routinely acquired T1-weighted MRI using a 3D patch-based conditional generative adversarial network and evaluated the performance of synthesized CT (sCT) images for treatment planning with tFUS. We compared the performance of sCT with real CT (rCT

SUBMITTER: Liu H 

PROVIDER: S-EPMC10514703 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature