Metallosis after Hip Arthroplasty Damages Skeletal Muscle: A Case Report.

ABSTRACT: Good musculoskeletal quality dramatically influences the outcome of an arthroplasty operation in geriatric patients, as well as is a key element for optimal osseointegration. In this context, metallosis is a complication associated with the type of prosthesis used, as implants with a chromium-cobalt interface are known to alter the bone microarchitecture and reduce the ratio of muscle to fat, resulting in lipid accumulation. Therefore, the aim of our study was to investigate possible muscle changes by histological, morphometric, and immunohistochemical analyses in a patient undergoing hip replacement revision with elevated blood and urinary concentrations of chromium and cobalt. Interestingly, the muscle tissue showed significant structural changes and a massive infiltration of adipose tis

SUBMITTER: Bonanni R 

PROVIDER: S-EPMC10514854 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature