Long non-coding RNA CASC7 is a promising serum biomarker for hepatocellular carcinoma.

ABSTRACT:

Background

At present, a large number of studies have found that long non-coding RNAs (lncRNAs) can be used as biomarkers for diagnosis and monitoring prognosis of hepatocellular carcinoma (HCC). The expression of lncRNA cancer susceptibility candidate 7 (CASC7) in HCC has rarely been studied. The purpose of this study was to explore the expression of CASC7 and its correlation with clinical features, and to further analyze its diagnostic value in HCC.

Methods

Serum samples were collected from 80 patients with HCC, 80 patients with chronic hepatitis B (CHB), and 80 healthy people. The expression level of serum CASC7 was detected by droplet digital PCR. Appropriate parametric and nonparametric tests were used for data analysis.

Results

The results showed that the expres

SUBMITTER: Liao L 

PROVIDER: S-EPMC10514991 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature