Exosomes as biomarkers and therapy in type 2 diabetes mellitus and associated complications.

ABSTRACT: Type 2 diabetes mellitus (T2DM) is one of the most prevalent metabolic disorders worldwide. However, T2DM still remains underdiagnosed and undertreated resulting in poor quality of life and increased morbidity and mortality. Given this ongoing burden, researchers have attempted to locate new therapeutic targets as well as methodologies to identify the disease and its associated complications at an earlier stage. Several studies over the last few decades have identified exosomes, small extracellular vesicles that are released by cells, as pivotal contributors to the pathogenesis of T2DM and its complications. These discoveries suggest the possibility of novel detection and treatment methods. This review provides a comprehensive presentation of exosomes that hold potential as novel biomarker

SUBMITTER: Satyadev N 

PROVIDER: S-EPMC10515224 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature