Polymorphic Solid Solutions in Molecular Crystals: Tips, Tricks, and Switches.

ABSTRACT: Crystal polymorphism has been a topic of much interest for the past 20 years or so, especially since its scientific (and legal) importance to the pharmaceutical industry was realized. By contrast, the formation of solid solutions in molecular crystals has been overlooked despite its long-standing prevalence in the analogous field of inorganic crystals. Wilfully forgotten, crystalline molecular solid solutions may be very common in our world since molecular compounds are rarely produced with 100% purity, and impurities able to form solid solutions are difficult to reject via recrystallization. Given the importance of both polymorphism and solid solutions in molecular crystals, we share here some tips, tricks, and observations to aid in their understanding. First, we propose a nomenclature s

SUBMITTER: Hill A 

PROVIDER: S-EPMC10515635 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature