Ontology highlight
ABSTRACT:
SUBMITTER: Mohamed M
PROVIDER: S-EPMC10515643 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Mohamed Myar M Klenke Anastasia K AK Anokhin Maksim V MV Amadou Harouna H Bothwell Paige J PJ Conroy Brigid B Nesterov Evgueni E EE Nesterova Irina V IV
ACS sensors 20230303 3
In this study, we report a general approach to the design of a new generation of small-molecule sensors that produce a zero background but are brightly fluorescent in the near-IR spectral range upon selective interaction with a biomolecular target. We developed a fluorescence turn-on/-off mechanism based on the aggregation/deaggregation of phthalocyanine chromophores. As a proof of concept, we designed, prepared, and characterized sensors for in-cell visualization of epidermal growth factor rece ...[more]