Timing and location of speech errors induced by direct cortical stimulation.

ABSTRACT: Cortical regions supporting speech production are commonly established using neuroimaging techniques in both research and clinical settings. However, for neurosurgical purposes, structural function is routinely mapped peri-operatively using direct electrocortical stimulation. While this method is the gold standard for identification of eloquent cortical regions to preserve in neurosurgical patients, there is lack of specificity of the actual underlying cognitive processes being interrupted. To address this, we propose mapping the temporal dynamics of speech arrest across peri-sylvian cortices by quantifying the latency between stimulation and speech deficits. In doing so, we are able to substantiate hypotheses about distinct region-specific functional roles (e.g., planning versus motor exe

SUBMITTER: Kabakoff H 

PROVIDER: S-EPMC10515921 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature