TMKit: a Python interface for computational analysis of transmembrane proteins.

ABSTRACT: Transmembrane proteins are receptors, enzymes, transporters and ion channels that are instrumental in regulating a variety of cellular activities, such as signal transduction and cell communication. Despite tremendous progress in computational capacities to support protein research, there is still a significant gap in the availability of specialized computational analysis toolkits for transmembrane protein research. Here, we introduce TMKit, an open-source Python programming interface that is modular, scalable and specifically designed for processing transmembrane protein data. TMKit is a one-stop computational analysis tool for transmembrane proteins, enabling users to perform database wrangling, engineer features at the mutational, domain and topological levels, and visualize protein-pro

SUBMITTER: Sun J 

PROVIDER: S-EPMC10516361 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature