Post-Illumination Pupil Response and Sleep Quality in Patients With Glaucoma: The LIGHT Study.

ABSTRACT:

Purpose

This study aimed to investigate whether intrinsically photosensitive retinal ganglion cell function evaluated using post-illumination pupil response (PIPR) in patients with glaucoma is associated with sleep quality.

Methods

This cross-sectional study measured the PIPR in 138 patients with glaucoma (mean age, 70.3 years) using pupil diameter after red and blue light exposure. The net PIPR change was classified into three groups according to tertiles (i.e., low, intermediate, and high groups), with lower net PIPR change indicating lower intrinsically photosensitive retinal ganglion cell (ipRGC) function. Subjective and objective sleep qualities were assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire and actigraphy, respectively, with a total PSQI sc

SUBMITTER: Jimura H 

PROVIDER: S-EPMC10516763 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature