Coronavirus Disease 2019 (COVID-19) Pandemic Lifestyle Changes May Have Influenced Small Bowel Microbial Composition and Microbial Resistance.

ABSTRACT:

Background

The coronavirus disease 2019 (COVID-19) global pandemic necessitated many severe lifestyle changes, including lockdowns, social distancing, altered food consumption and exercise patterns, and extensive hygiene practices. These extensive changes may have affected the human gut microbiome, which is highly influenced by lifestyle.

Aims

To examine the potential effects of pandemic-related lifestyle changes on the metabolically relevant small bowel microbiome.

Methods

Adult subjects presenting for upper endoscopy without colonoscopy were identified and divided into two matched groups: pre-pandemic (February 2019-March 2020) and intra-pandemic (April 2021-September 2021, all COVID-19 negative). Duodenal aspirates and blood samples were collected. Duodenal microbi

SUBMITTER: Hosseini A 

PROVIDER: S-EPMC10516792 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature