Characterizing functional modules in the human thalamus: coactivation-based parcellation and systems-level functional decoding.

ABSTRACT: The human thalamus relays sensory signals to the cortex and facilitates brain-wide communication. The thalamus is also more directly involved in sensorimotor and various cognitive functions but a full characterization of its functional repertoire, particularly in regard to its internal anatomical structure, is still outstanding. As a putative hub in the human connectome, the thalamus might reveal its functional profile only in conjunction with interconnected brain areas. We therefore developed a novel systems-level Bayesian reverse inference decoding that complements the traditional neuroinformatics approach towards a network account of thalamic function. The systems-level decoding considers the functional repertoire (i.e., the terms associated with a brain region) of all regions showing c

SUBMITTER: Boeken OJ 

PROVIDER: S-EPMC10516793 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature