Association Between Blood Lead Levels and Thyroid Function: An Updated Systematic Review and Meta-Analysis.

ABSTRACT: Chronic Lead (Pb) exposure is associated with disrupting certain endocrine levels and is referred to as an endocrine disruptor. Thyroid hormones, involved in regulating numerous physiological functions, are reported with conflicting associations with chronic Pb exposure. This study broadly evaluated the association between long-term lead exposure and thyroid function parameters. In this systematic review, the observational studies documenting the changes in thyroid function parameters between the chronically Pb-exposed and controls were systematically identified from PubMed-Medline, Scopus, and Embase digital databases from the beginning to March 31, 2022. The protocol was previously registered with PROSPERO (ID: CRD42022315520) and executed following PRISMA 2020 guidelines. The random-eff

SUBMITTER: Balachandar R 

PROVIDER: S-EPMC10516803 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature