Changes in salivary microbiota due to gastric cancer resection and its relation to gastric fluid microbiota.

ABSTRACT: Gastric cancer is one of the leading causes of death worldwide, and resections are performed to cure the disease. We have previously reported the changes in the gastric microbiota after gastric cancer resection, which may be associated with the oral microbiota; however, the changes in the oral microbiota remain uncharacterized. This study aimed to characterize the changes in the salivary microbiota caused by gastric cancer resection and to evaluate their association with the gastric fluid microbiota. Saliva and gastric fluid samples were collected from 63 patients who underwent gastrectomy before and after surgery, and a 16S rRNA metagenomic analysis was performed to compare the microbiota composition. The number of bacterial species in the salivary microbiota decreased, and the bacterial

SUBMITTER: Komori E 

PROVIDER: S-EPMC10516953 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature