Optical coherence tomography angiography in Parkinson's disease: a systematic review and meta-analysis.

ABSTRACT:

Background

To examine the association between optical coherence tomography angiography (OCTA) retinal measurements and Parkinson's disease (PD).

Methods

We searched MEDLINE and EMBASE from inception up to November 5th, 2021 for studies examining the differences between OCTA retinal measurements in PD patients and healthy controls. We used the Hartung-Knapp-Sidik-Jonkman random-effects method to combine study-specific standardized mean differences (SMD) in pooled effect estimates and a meta-analytic extension of the E-value metric to quantify the confounding bias capable of nullifying the pooled estimates.

Results

Nine eligible studies for our systematic review were identified through our search strategy. The pooled SMD between the retinal vessel density of PD patients

SUBMITTER: Katsimpris A 

PROVIDER: S-EPMC10516969 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature