Drug-induced social connection: both MDMA and methamphetamine increase feelings of connectedness during controlled dyadic conversations.

ABSTRACT: MDMA is a stimulant-like drug with distinctive empathogenic effects. Its pro-social effects, such as feelings of connectedness, may contribute to both its popularity as a recreational drug and its apparent value as an adjunct to psychotherapy. However, little is known about the behavioral processes by which MDMA affects social interactions. This investigation examined the effects of MDMA (100 mg versus placebo; N = 18) on feelings of connectedness with an unfamiliar partner during a semi-structured casual conversation. A separate study examined the effects of a prototypic stimulant methamphetamine (MA; 20 mg versus placebo; N = 19) to determine the pharmacological specificity of effects. Oxytocin levels were obtained in both studies. Compared to placebo, both MDMA and MA increased feelings

SUBMITTER: Molla H 

PROVIDER: S-EPMC10516994 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature