Clinical Instability Is a Sign of Severity of Illness: A Cohort Study.

ABSTRACT:

Objectives

Test the hypothesis that within patient clinical instability measured by deterioration and improvement in mortality risk over 3-, 6-, 9-, and 12-hour time intervals is indicative of increasing severity of illness.

Design

Analysis of electronic health data from January 1, 2018, to February 29, 2020.

Setting

PICU and cardiac ICU at an academic children's hospital.

Patients

All PICU patients. Data included descriptive information, outcome, and independent variables used in the Criticality Index-Mortality.

Interventions

None.

Measurements and main results

There were 8,399 admissions with 312 deaths (3.7%). Mortality risk determined every three hours using the Criticality Index-Mortality, a machine learning algorithm calibrated to this hospi

SUBMITTER: Pollack MM 

PROVIDER: S-EPMC10517068 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature