Efficient approximate signal reconstruction for correction of gradient nonlinearities in diffusion-weighted imaging.

ABSTRACT: In diffusion weighted MRI (DW-MRI), hardware nonlinearities lead to spatial variations in the orientation and magnitude of diffusion weighting. While the correction of these spatial distortions has been well established for analyses of DW-MRI, the existing voxel-wise empirical correction for gradient nonlinearities requires reimplementation of existing models, as the resultant gradients vary by voxel. Herein, we propose a two-step signal approximation after voxel-wise correction of gradient nonlinearity effects in DW-MRI. The proposed technique (1) scales the diffusion signal and (2) resamples the gradient orientations. This results in uniform gradients across the corrected image and provides the key advantage of seamless integration into current diffusion workflows. We investigated the va

SUBMITTER: Kanakaraj P 

PROVIDER: S-EPMC10517071 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature