Infectious Complications of Lung Transplant for Coronavirus Disease 2019-Associated Lung Injury: A Single-Center Case-Control Cohort Study.

ABSTRACT:

Background

Lung transplantation is one of the only options for patients with severe coronavirus disease 2019 (COVID-19)-associated lung injury (CALI). Studies on patients who received a lung transplant for CALI have, to date, not looked at the infectious outcomes.

Methods

After institutional review board approval, a retrospective case-control cohort study, matched 1:1, collected data on patients who underwent lung transplantation for CALI (case) and for non-COVID-19 end-stage lung disease (control) between 1 June 2020 and 1 April 2022 at a large academic hospital in Chicago. We assessed infectious complications and other key outcomes pre-transplant and for 1 year post-transplant.

Results

Among 78 patients (39 CALI and 39 matched control lung transplant patients), thos

SUBMITTER: Osborn R 

PROVIDER: S-EPMC10517091 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature