Season of Conception and Risk of Cerebral Palsy.

ABSTRACT:

Importance

Cerebral palsy (CP) is the most prevalent neuromotor disability in childhood, but for most cases the etiology remains unexplained. Seasonal variation in the conception of CP may provide clues for their potential etiological risk factors that vary across seasons.

Objective

To evaluate whether the month or season of conception is associated with CP occurrence.

Design, setting, and participants

This statewide cohort study examined more than 4 million live births that were registered in the California birth records during 2007 to 2015 and were linked to CP diagnostic records (up to year 2021). Statistical analyses were conducted between March 2022 and January 2023.

Exposures

The month and season of conception were estimated based on the child's date of b

SUBMITTER: Zhuo H 

PROVIDER: S-EPMC10517373 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature