Multi-functional conductive hydrogels based on heparin-polydopamine complex reduced graphene oxide for epidermal sensing and chronic wound healing.

ABSTRACT: Flexible hydrogel sensors have expanded the applications of electronic devices due to their suitable mechanical properties and excellent biocompatibility. However, conventionally synthesized reduced graphene oxide (rGO) encounters limitations in reduction degree and dispersion, restricting the conductivity of graphene hydrogels and impeding the development of high-sensitivity flexible sensors. Moreover, hydrogels are susceptible to inflammation and bacterial infections, jeopardizing sensor stability over time. Thus, the challenge persists in designing conductive hydrogels that encompass high sensitivity, antibacterial efficacy, and anti-oxidative capabilities. In this study, GO was modified and reduced via a heparin-polydopamine (Hep-PDA) complex, yielding well-reduced and uniformly disper

SUBMITTER: Dou Y 

PROVIDER: S-EPMC10517544 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature