The epidemiological and genetic characteristics of human parvovirus B19 in patients with febrile rash illnesses in China.

ABSTRACT: To understand the epidemiological and genetic characteristics of B19V, a multiple-province surveillance of patients with febrile rash illnesses (FRIs) were conducted in China during 2009 ~ 2021. The clinical specimens of 3,820 FRI patients were collected and tested for B19V DNA. A total of 99 (2.59%) patients were positive for B19V, and 49 (49.49%) were children under 5 years old. B19V infections occurred throughout the year without obvious seasonal pattern. Ten NS1-VP1u sequences and seven genome sequences were obtained in this study, identified as subgenotype 1a. Combined with the globally representative genome sequences, no temporal and geographic clustering trends of B19V were observed, and there was no significant correlation between B19V sequences and clinical manifestations. The evo

SUBMITTER: Jiang H 

PROVIDER: S-EPMC10517975 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature