EPlatypus: an ecosystem for computational analysis of immunogenomics data.

ABSTRACT:

Motivation

The maturation of systems immunology methodologies requires novel and transparent computational frameworks capable of integrating diverse data modalities in a reproducible manner.

Results

Here, we present the ePlatypus computational immunology ecosystem for immunogenomics data analysis, with a focus on adaptive immune repertoires and single-cell sequencing. ePlatypus is an open-source web-based platform and provides programming tutorials and an integrative database that helps elucidate signatures of B and T cell clonal selection. Furthermore, the ecosystem links novel and established bioinformatics pipelines relevant for single-cell immune repertoires and other aspects of computational immunology such as predicting ligand-receptor interactions, structural modeling

SUBMITTER: Cotet TS 

PROVIDER: S-EPMC10518073 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature