Microbes are potential key players in the evolution of life histories and aging in Caenorhabditis elegans.

ABSTRACT: Microbes can have profound effects on host fitness and health and the appearance of late-onset diseases. Host-microbe interactions thus represent a major environmental context for healthy aging of the host and might also mediate trade-offs between life-history traits in the evolution of host senescence. Here, we have used the nematode Caenorhabditis elegans to study how host-microbe interactions may modulate the evolution of life histories and aging. We first characterized the effects of two non-pathogenic and one pathogenic Escherichia coli strains, together with the pathogenic Serratia marcescens DB11 strain, on population growth rates and survival of C. elegans from five different genetic backgrounds. We then focused on an outbred C. elegans<

SUBMITTER: Santos J 

PROVIDER: S-EPMC10518755 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature