Mechanical Power Correlates With Stress, Strain, and Atelectrauma Only When Normalized to Aerated Lung Size in Patients With Acute Respiratory Distress Syndrome.

ABSTRACT:

Objectives

First, to investigate whether the severity of acute respiratory distress syndrome (ARDS) influences ventilator-induced lung injury (VILI) risk in ventilated patients with similar mechanical power of respiratory system (MP_RS). Second, to determine whether, under these circumstances, there is a relationship between transpulmonary mechanical power (MP_Tp) normalized to the aerated lung (specific lung mechanical power or SLMP) and VILI risk, and third, to determine whether normalizing MP_RS to compliance of respiratory system (CRS) can replace SLMP to bedside.

Design

Prospective cohort study.

Setting

The study was conducted in a tertiary academic ICU.

Patients

The study included 18 patients with ARDS.

Interventions

V

SUBMITTER: Pistillo N 

PROVIDER: S-EPMC10519489 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature