Categorical versus dimensional structure of autism spectrum disorder: A multi-method investigation.

ABSTRACT:

Background

A key question for any psychopathological diagnosis is whether the condition is continuous or discontinuous with typical variation. The primary objective of this study was to use a multi-method approach to examine the broad latent categorical versus dimensional structure of autism spectrum disorder (ASD).

Method

Data were aggregated across seven independent samples of participants with ASD, other neurodevelopmental disorders (NDD), and non-ASD/NDD controls (aggregate Ns = 512-16,755; ages 1.5-22). Scores from four distinct phenotype measures formed composite "indicators" of the latent ASD construct. The primary indicator set included eye gaze metrics from seven distinct social stimulus paradigms. Logistic regressions were used to combine gaze metrics within

SUBMITTER: Frazier TW 

PROVIDER: S-EPMC10519739 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature