Late-onset MELAS syndrome in a 46-year-old man with initial symptom of chest tightness: a case report.

ABSTRACT:

Background

Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like episodes (MELAS) syndrome is a rare mitochondrial disorder caused by mutations in mitochondrial DNA, resulting in impaired energy production and affecting multiple organs. We present a suspected MELAS syndrome case with the initial symptom of chest tightness.

Case summary

A 46-year-old man sought medical attention due to progressively worsening chest tightness during physical activity. He had been receiving treatment for type 2 diabetes for 15 years. One year ago, he presented with symptoms of hearing impairment. Transthoracic echocardiography revealed increased thickness of the left ventricular wall. Serum protein electrophoresis showed no evidence of light-chain amyloidosis, and the 99mTc-3,3-diph

SUBMITTER: Wang A 

PROVIDER: S-EPMC10519872 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature