Cardioprotective effect of antiviral therapy among hepatitis C infected patients: A meta-analysis.

ABSTRACT:

Background

Hepatitis C (HCV) infections have been shown to be associated a with higher risk of atherosclerotic cardiovascular disease (CVD). However, the use of antiviral therapy (AVT) and the risk of CVD has not been well established with limited literature.

Objective

We sought to evaluate the association between AVT use post-HCV infection and cardiovascular outcomes.

Methods

We performed a systematic literature search using PubMed, Embase, and Scopus for relevant articles from inception until 10th March 2023. Primary clinical outcomes were the incidence of any CVD. Secondary endpoints were all-cause of mortality, stroke, myocardial infarction, and peripheral artery disease.

Results

A total of 394,452 patients were included in the analysis (111,076 in the AVT

SUBMITTER: Jaiswal V 

PROVIDER: S-EPMC10520301 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature