A cross-sectional study of cognitive performance in bipolar disorder across the lifespan: the cog-BD project.

ABSTRACT:

Background

Neuroprogressive models of the trajectory of cognitive dysfunction in patients with bipolar disorder (BD) have been proposed. However, few studies have explored the relationships among clinical characteristics of BD, cognitive dysfunction, and aging.

Methods

We conducted a cross-sectional analysis in euthymic participants with the MATRICS Cognitive Consensus Battery, the Trail Making Test B, the Stroop Test, and the Wechsler Test of Adult Reading. Age- and gender-equated control participants without a mental disorder ['Healthy Controls' - HC)] were assessed similarly. We compared cognitive performance both globally and in seven domains in four groups: younger BD (age ⩽49 years; n = 70), older BD (age ⩾50 years; n = 48), younger HC (n = 153), a

SUBMITTER: Jones BDM 

PROVIDER: S-EPMC10520592 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature