New-Onset Age of Nonalcoholic Fatty Liver Disease and Cancer Risk.

ABSTRACT:

Importance

The onset age of nonalcoholic fatty liver disease (NAFLD) is decreasing, and whether earlier ages of NAFLD onset are associated with increased cancer risk is currently unclear.

Objective

To explore the association between NAFLD new-onset age and cancer risk.

Design, setting, and participants

This cohort study was conducted among 179 328 participants included in the Kailuan Cohort Study between 2006 and 2021. In total, 46 100 incident NAFLD cases were identified. For each case, a participant matched by age (older or younger by 1 year) and sex was randomly selected to create a new matched study cohort. Data were analyzed from December 2022 through April 2023.

Exposure

Onset of NAFLD.

Main outcomes and measures

The association between the onset a

SUBMITTER: Liu C 

PROVIDER: S-EPMC10520743 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature