Lytic polysaccharide monooxygenase synergized with lignin-degrading enzymes for efficient lignin degradation.

ABSTRACT: Even though the discovery of lytic polysaccharide monooxygenases (LPMOs) has fundamentally shifted our understanding of biomass degradation, most of the current studies focused on their roles in carbohydrate oxidation. However, no study demonstrated if LPMO could directly participate to the process of lignin degradation in lignin-degrading microbes. This study showed that LPMO could synergize with lignin-degrading enzymes for efficient lignin degradation in white-rot fungi. The transcriptomics analysis of fungi Irpex lacteus and Dichomitus squalens during their lignocellulosic biomass degradation processes surprisingly highlighted that LPMOs co-regulated with lignin-degrading enzymes, indicating their more versatile roles in the redox network. Biochemical analysis further con

SUBMITTER: Sun S 

PROVIDER: S-EPMC10520884 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature