Pilot Study to Gain First Indications for the Impact of a 3-Month's Oral Intake of a Sucrosomial Iron Supplement on Hemoglobin in Iron-Deficient Blood Donors.

ABSTRACT:

Introduction

Regular whole blood donors often suffer from iron deficiency (ID) or iron deficiency anemia due to the loss of 200-300 mg of iron with each donation. Hemoglobin (Hb) as donor eligibility criterion reflects iron stores only poorly. ID in blood donors is typically prevented or treated with orally administered ferrous salts, which frequently cause gastrointestinal side effects. A high daily oral iron dose is counterproductive due to hepcidin upregulation. Oral sucrosomial iron (_sucriron) is encapsulated ferric pyrophosphate that may be an option for blood donors due to its supposed high bioavailability and good tolerability.

Methods

This monocentric single-cohort pilot study included fifty whole blood donors (divided into premenopausal women, postmenopau

SUBMITTER: Torreiter PP 

PROVIDER: S-EPMC10521237 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature