Serum metabolite profiling reveals metabolic characteristics of sepsis patients using LC/MS-based metabolic profiles: a cross-sectional study.

ABSTRACT:

Background

Individuals with sepsis exhibited a higher likelihood of benefiting from early initiation of specialized treatment to enhance the prognosis of the condition. The objective of this study is to identify potential biomarkers of sepsis by means of serum metabolomics.

Materials and methods

The screening of putative biomarkers of sepsis was conducted using serum samples from patients with sepsis and a control group of healthy individuals. The pathogenesis of sepsis was determined through the utilization of liquid chromatography-mass spectrometry-based metabolic profiles and bioinformatic techniques, which in turn provided a foundation for timely diagnosis and intervention.

Results

Individuals with sepsis had significantly different metabolic characteristics compa

SUBMITTER: Peng J 

PROVIDER: S-EPMC10521453 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature