Sonometric assessment of cough predicts extubation failure: SonoWean-a proof-of-concept study.

ABSTRACT:

Background

Extubation failure is associated with increased mortality. Cough ineffectiveness may be associated with extubation failure, but its quantification for patients undergoing weaning from invasive mechanical ventilation (IMV) remains challenging.

Methods

Patients under IMV for more than 24 h completing a successful spontaneous T-tube breathing trial (SBT) were included. At the end of the SBT, we performed quantitative sonometric assessment of three successive coughing efforts using a sonometer. The mean of the 3-cough volume in decibels was named Sonoscore.

Results

During a 1-year period, 106 patients were included. Median age was 65 [51-75] years, mainly men (60%). Main reasons for IMV were acute respiratory failure (43%), coma (25%) and shock (17%). Median du

SUBMITTER: Bonny V 

PROVIDER: S-EPMC10521471 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature