Genome-wide landscape of runs of homozygosity and differentiation across Egyptian goat breeds.

ABSTRACT: Understanding the genomic features of livestock is essential for successful breeding programs and conservation. This information is scarce for local goat breeds in Egypt. In the current study, genomic regions with selection signatures were identified as well as runs of homozygosity (ROH), genomic inbreeding coefficients (F_ROH) and fixation index (F_ST) were detected in Egyptian Nubian, Damascus, Barki and Boer goat breeds. A total of 46,268 SNP markers and 337 animals were available for the genomic analyses. On average, 145.44, 42.02, 87.90 and 126.95 ROHs were detected per individual in the autosomal genome of the respective breeds. The mean accumulative ROH lengths ranged from 46.5 Mb in Damascus to 360 Mb in Egyptian Nubian. The short ROH segments (< 2 Mb) were most

SUBMITTER: Sallam AM 

PROVIDER: S-EPMC10521497 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature