Antifungal activity of Lysinibacillus macroides against toxigenic Aspergillus flavus and Fusarium proliferatum and analysis of its mycotoxin minimization potential.

ABSTRACT:

Background

Toxigenic fungi (Aspergillus and Fusarium) and their metabolites represent the major cause of corn and corn-based products contamination and consequently lead to severe economic and health issues.

Aim

Our current study aimed to investigate the efficacy of using L. macroides Bac6 as a biological control agent against the toxigenic fungi; A. flavus f10 and F. proliferatum f30 and their mycotoxins.

Results

The results illustrated that A. flavus f10 produced the aflatoxins AFB₁ and AFG₂ with concentrations of 21.239 and 13.593 ppb, respectively. While F. proliferatum f30 produced fumonisin B₁ (9600 ppb). Furthermore, L. macroides showed a high potential for inhibition of toxigenic fungal growth using a dual culture method. F. pr

SUBMITTER: Mahmoud ALE 

PROVIDER: S-EPMC10521556 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature