The clinical-histologic and prognostic characteristics in patients with a second primary non-small-cell lung cancer after a lobectomy.

ABSTRACT:

Objectives

The goal of this study was to investigate whether an operation can offer survival benefits for patients with a second primary non-small-cell lung cancer (NSCLC) after a lobectomy for a first primary NSCLC and to analyse the characteristics affecting the survival of those patients.

Methods

We performed survival analyses of patients with a second primary NSCLC based on the Surveillance, Epidemiology and End Results program and used propensity score matching to reduce the potential bias and analyse the data. In addition, the primary observational end point was overall survival (OS), and the secondary observational end point was histologic migration.

Results

The data from 944 patients were used to perform the main analysis. A total of 36.2% of patients experien

SUBMITTER: Wu LL 

PROVIDER: S-EPMC10521628 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature