Making Use of Plant uORFs to Control Transgene Translation in Response to Pathogen Attack.

ABSTRACT: Reducing crop loss to diseases is urgently needed to meet increasing food production challenges caused by the expanding world population and the negative impact of climate change on crop productivity. Disease-resistant crops can be created by expressing endogenous or exogenous genes of interest through transgenic technology. Nevertheless, enhanced resistance by overexpressing resistance-produced genes often results in adverse developmental affects. Upstream open reading frames (uORFs) are translational control elements located in the 5' untranslated region (UTR) of eukaryotic mRNAs and may repress the translation of downstream genes. To investigate the function of three uORFs from the 5'-UTR of ACCELERATED CELL 11 (uORFs_ACD11), we develop a fluorescent reporter system and

SUBMITTER: Ai G 

PROVIDER: S-EPMC10521741 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature