Association between cumulative exposure periods of flupentixol or any antipsychotics and risk of lung cancer.

ABSTRACT:

Background

Preclinical evidence suggests that certain antipsychotic medications may inhibit the development of lung cancer. This study aims to investigate the association between incident lung cancer and different cumulative exposure periods of flupentixol or any antipsychotics.

Methods

Using electronic health records from the Hospital Authority in Hong Kong, this nested case-control study included case participants aged 18 years or older with newly diagnosed lung cancer after initiating antipsychotics between January 1, 2003, and August 31, 2022. Each case was matched to up to ten controls of the same sex and age, who were also antipsychotic users. Multivariable conditional logistic regression models were conducted to quantify the association between lung cancer and differe

SUBMITTER: Chai Y 

PROVIDER: S-EPMC10522572 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature