Utility of ElastPQ point-shear wave elastography in the work-up of patients with primary sclerosing cholangitis.

ABSTRACT:

Background & aims

Liver stiffness measurement (LSM) and spleen stiffness measurement (SSM) have been shown to be useful tools for assessing the risk of fibrosis and portal hypertension, respectively. However, data on the accuracy of LSM and SSM measured by point-shear wave elastography (pSWE) in patients affected by primary sclerosing cholangitis (PSC) are still lacking. Thus, we aimed to prospectively assess their performance in a cohort of patients with PSC.

Methods

We determined the correlation between LSM assessed by a pSWE technique (ElastPQ) and by FibroScan-transient elastography (F-TE). Furthermore, we used receiver-operating characteristic curves and area under the curves (AUROC) to evaluate the performance of LSM by ElastPQ for the staging of fibrosis, using F-TE a

SUBMITTER: Roccarina D 

PROVIDER: S-EPMC10522908 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature