Conditional Risks of Biochemical Failure and Prostate Cancer-Specific Death in Patients Undergoing External Beam Radiotherapy: A Secondary Analysis of 2 Randomized Clinical Trials.

ABSTRACT:

Importance

As patients achieve years of survival after treatment for prostate cancer, the risk of biochemical failure (BF) or prostate cancer-specific death (PCSD) may evolve over time, with clinical relevance to both patients and clinicians.

Objective

To determine conditional BF-free survival, PSCD, and overall survival estimates for patients with low- or intermediate-risk prostate cancer enrolled in the Radiation Therapy Oncology Group (RTOG) 0126 and RTOG 0415 clinical trials. A secondary objective was to determine whether prognostic factors at diagnosis remain relevant at later points in follow-up.

Design, setting, and participants

A pooled secondary analysis of patients treated with external-beam radiotherapy alone and enrolled in the prospective randomized clini

SUBMITTER: Alexander GS 

PROVIDER: S-EPMC10523164 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature