Impact of the Severe acute respiratory syndrome coronavirus 2 pandemic on mortality associated with healthcare-associated infections.

ABSTRACT:

Objective

To determine the relationship between severe acute respiratory syndrome coronavirus 2 infection, hospital-acquired infections (HAIs), and mortality.

Design

Retrospective cohort.

Setting

Three St. Louis, MO hospitals.

Patients

Adults admitted ≥48 hours from January 1, 2017 to August 31, 2020.

Methods

Hospital-acquired infections were defined as those occurring ≥48 hours after admission and were based on positive urine, respiratory, and blood cultures. Poisson interrupted time series compared mortality trajectory before (beginning January 1, 2017) and during the first 6 months of the pandemic. Multivariable logistic regression models were fitted to identify risk factors for mortality in patients with an HAI before and during the pandemic. A time-

SUBMITTER: Atkinson A 

PROVIDER: S-EPMC10523544 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature