Effectiveness of Hepatitis B Vaccination for Patients With Inflammatory Bowel and Celiac Disease.

ABSTRACT:

Background & aims

Guidelines recommend measuring antibody (Ab) titers to hepatitis B virus (HBV) after vaccination for patients with inflammatory bowel disease (IBD) or celiac disease (CD) ("patients with IBD/CD") and revaccinating when titers are low. Few data, however, support this recommendation. We aimed to compare effectiveness of HBV vaccination (immunity and infection rates) for patients with IBD/CD vs matched referents.

Methods

Using the Rochester Epidemiology Project, we performed a retrospective cohort study of patients first diagnosed with IBD/CD (index date) while residing in Olmsted County, Minnesota, from January 1, 2000, through December 31, 2019. HBV screening results were obtained from health records.

Results

In 1264 incident cases of IBD/CD, only 6 H

SUBMITTER: Ulrich JA 

PROVIDER: S-EPMC10523860 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature