Long-term Risks of Depression and Suicide Among Men with Prostate Cancer: A National Cohort Study.

ABSTRACT:

Background

A diagnosis of prostate cancer (PC) may cause psychosocial distress that worsens quality of life; however, long-term mental health outcomes are unclear.

Objective

To determine the long-term risks of major depression and death by suicide in a large population-based cohort.

Design, setting, and participants

This was a national cohort study of 180 189 men diagnosed with PC during 1998-2017 and 1 801 890 age-matched, population-based, control men in Sweden.

Outcome measurements and statistical analysis

Major depression and death by suicide were ascertained from nationwide outpatient, inpatient, and death records up to 2018. Cox regression was used to compute hazard ratios (HRs) adjusted for sociodemographic factors and comorbidities. Subanalyses assessed

SUBMITTER: Crump C 

PROVIDER: S-EPMC10523908 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature