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Benefits and harms of breast cancer screening: Cohort study of breast cancer mortality and overdiagnosis.


ABSTRACT:

Background

Quantifying the benefits and harms of breast cancer screening accurately is important for planning and evaluating screening programs and for enabling women to make informed decisions about participation. However, few cohort studies have attempted to estimate benefit and harm simultaneously.

Aims

We aimed to quantify the impact of mammographic screening on breast cancer mortality and overdiagnosis using a cohort of women invited to attend Australia's national screening program, BreastScreen.

Methods

In a cohort of 41,330 women without prior breast cancer diagnosis, screening, or diagnostic procedures invited to attend BreastScreen Western Australia in 1994-1995, we estimated the cumulative risk of breast cancer mortality and breast cancer incidence (invasive

SUBMITTER: Wang S 

PROVIDER: S-EPMC10524083 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature