Functional proteins in breast milk and their correlation with the development of the infant gut microbiota: a study of mother-infant pairs.

ABSTRACT:

Introduction

Proteins in breast milk play an important role in the growth and development of infants. This study aims to explore the correlation between functional proteins in breast milk and the infant gut microbiota.

Methods

Twenty-three mothers and their infants were enrolled and breast milk samples and infant fecal samples were collected. Breast milk protein content was determined by UPLC-MS/MS, and 16S rRNA sequencing was employed to analyze the gut microbiota of infant.

Results

The results indicated that the secretory immunoglobulin A (sIgA) content in breast milk was positively correlated with the abundance of Veillonella parvula. The κ-casein content was positively correlated with the abundance of Clostridium butyricum. The osteopontin (OPN) and

SUBMITTER: Xi M 

PROVIDER: S-EPMC10524269 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature