SCORE2 Report 24: Nonlinear Relationship of Retinal Thickness and Visual Acuity in Central Retinal and Hemiretinal Vein Occlusion.

ABSTRACT:

Purpose

To investigate whether a nonlinear association between central subfield thickness (CST) on spectral-domain OCT and concurrent visual acuity letter score (VALS) exists in eyes treated initially with aflibercept or bevacizumab for macular edema associated with central retinal vein occlusion (CRVO) or hemiretinal vein occlusion (HRVO) in the Study of Comparative Treatments for Retinal Vein Occlusion 2 (SCORE2).

Design

Long-term follow-up after a randomized clinical trial from 64 centers in the United States.

Participants

Participants were followed up to 60 months and treated at investigator discretion after completing the 12-month treatment protocol.

Methods

Two-segment linear regression models were compared with simple linear regression models of VALS on

SUBMITTER: Scott IU 

PROVIDER: S-EPMC10524366 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature